The world we live and work in has changed, and continues to change
rapidly. Clinical pharmacy is one area where change is at its most rapid,
and the extent and speed of change poses a major challenge. Although
this book covers a huge amount of ground, perhaps three main areas
stand out to a non-pharmacist looking over the pharmacist's shoulder.
The fi rst is the interpretation of clinical evidence about effi cacy (or
effectiveness) and harm of medicines. The number of new medicines, and
studies of existing medicines, is exploding, producing more information
than we can handle. The key to handling it is often to have good systematic
reviews of good randomized trials, when the results will be secure.

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